increased susceptibility to endotoxin shock_Stat3<tm1Xyfu>/Stat3<+>,Tg(Myh6-cre)2182Mds/0

http://metadb.riken.jp/0008735I129S1SvFVBNStat3tm1XyfuStat3TgMyh6cre2182Mds0TgMyh6cre2182MdsStat3Stat3tm1Xyfu

increased susceptibility to endotoxin shock_Stat3<tm1Xyfu>/Stat3<+>,Tg(Myh6-cre)2182Mds/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2182, Michael D Schneider
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447636
• signal transducer and activator of transcription 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:103038

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Stat3<tm1Xyfu>/Stat3<+>,Tg(Myh6-cre)2182Mds/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Myh6-cre)2182Mds|Stat3<+>|Stat3<tm1Xyfu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to endotoxin shock
  http://purl.obolibrary.org/obo/MP_0008735

文献

http://purl.org/net/cito/citesAsAuthority

• Jörg J. Jacoby, et.al., Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age., Proceedings of the National Academy of Sciences of the United States of America, 2003, 100
  http://rdf.ncbi.nlm.nih.gov/pubmed/14566054