increased susceptibility to endotoxin shock_Sigirr<tm1Lix>/Sigirr<tm1Lix>

http://metadb.riken.jp/0008735I129S6SvEvTacBALBcSigirrtm1LixSigirrtm1LixSigirrtm1Lix

increased susceptibility to endotoxin shock_Sigirr<tm1Lix>/Sigirr<tm1Lix>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
  http://metadb.riken.jp/db/mgi_rdf/MGI:1344402

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sigirr<tm1Lix>/Sigirr<tm1Lix>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sigirr<tm1Lix>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * BALB/c

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to endotoxin shock
  http://purl.obolibrary.org/obo/MP_0008735

文献

http://purl.org/net/cito/citesAsAuthority

• David. Wald, et.al., SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling., Nature immunology, 2003, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/12925853