increased susceptibility to endotoxin shock_Thbd<tm2.1Emc>/Thbd<tm2.1Emc>

http://metadb.riken.jp/0008735I129SvBALBcC57BL6Thbdtm21EmcThbdtm21EmcThbdtm21Emc

increased susceptibility to endotoxin shock_Thbd<tm2.1Emc>/Thbd<tm2.1Emc>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• thrombomodulin
  http://metadb.riken.jp/db/mgi_rdf/MGI:98736

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Thbd<tm2.1Emc>/Thbd<tm2.1Emc>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Thbd<tm2.1Emc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * BALB/c * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to endotoxin shock
  http://purl.obolibrary.org/obo/MP_0008735

文献

http://purl.org/net/cito/citesAsAuthority

• Edward M. Conway, et.al., The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways., The Journal of experimental medicine, 2002, 196
  http://rdf.ncbi.nlm.nih.gov/pubmed/12208873