abnormal immunoglobulin heavy chain V(D)J recombination_Ikzf1<tm1.1(Pax5)Mbu>/Ikzf1<+>,Tcf3<tm1Mbu>/Tcf3<tm1Mbu>,Tg(Vav1-icre)A2Kio/0

http://metadb.riken.jp/0008760I129P2OlaHsdC57BL10CBACaIkzf1tm11Pax5MbuIkzf1Tcf3tm1MbuTcf3tm1MbuTgVav1icreA2Kio0Ikzf1tm11Pax5MbuTgVav1icreA2KioTcf3tm1MbuIkzf1

abnormal immunoglobulin heavy chain V(D)J recombination_Ikzf1<tm1.1(Pax5)Mbu>/Ikzf1<+>,Tcf3<tm1Mbu>/Tcf3<tm1Mbu>,Tg(Vav1-icre)A2Kio/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transcription factor 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:98510
• transgene insertion A2, Dimitris Kioussis
  http://metadb.riken.jp/db/mgi_rdf/MGI:2449945
• IKAROS family zinc finger 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1342540

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ikzf1<tm1.1(Pax5)Mbu>/Ikzf1<+>,Tcf3<tm1Mbu>/Tcf3<tm1Mbu>,Tg(Vav1-icre)A2Kio/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ikzf1<tm1.1(Pax5)Mbu>|Tg(Vav1-icre)A2Kio|Tcf3<tm1Mbu>|Ikzf1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/10 * CBA/Ca

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal immunoglobulin heavy chain V(D)J recombination
  http://purl.obolibrary.org/obo/MP_0008760

文献

http://purl.org/net/cito/citesAsAuthority

• Kyongrim. Kwon, et.al., Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development., Immunity, 2008, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/18538592