abnormal fetal cardiomyocyte morphology_Hccs<tm1Tcc>/Hccs<+>,Nkx2-5<tm2(cre)Rph>/Nkx2-5<+>,Tg(CAG-EGFP)D4Nagy/0,Tg(Hmgcr-lacZ)H253Sest/0

http://metadb.riken.jp/0008788I129S1Sv129X1SvJC57BL6DBA2Hccstm1TccHccsNkx25tm2creRphNkx25TgCAGEGFPD4Nagy0TgHmgcrlacZH253Sest0Nkx25TgHmgcrlacZH253SestTgCAGEGFPD4NagyHccstm1TccHccsNkx25tm2creRph

abnormal fetal cardiomyocyte morphology_Hccs<tm1Tcc>/Hccs<+>,Nkx2-5<tm2(cre)Rph>/Nkx2-5<+>,Tg(CAG-EGFP)D4Nagy/0,Tg(Hmgcr-lacZ)H253Sest/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• holocytochrome c synthetase
  http://metadb.riken.jp/db/mgi_rdf/MGI:106911
• NK2 homeobox 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:97350
• transgene insertion H253, Seong-Seng Tan
  http://metadb.riken.jp/db/mgi_rdf/MGI:3826980
• transgene insertion D4, Andras Nagy
  http://metadb.riken.jp/db/mgi_rdf/MGI:3055028

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hccs<tm1Tcc>/Hccs<+>,Nkx2-5<tm2(cre)Rph>/Nkx2-5<+>,Tg(CAG-EGFP)D4Nagy/0,Tg(Hmgcr-lacZ)H253Sest/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nkx2-5<+>|Tg(Hmgcr-lacZ)H253Sest|Tg(CAG-EGFP)D4Nagy|Hccs<tm1Tcc>|Hccs<+>|Nkx2-5<tm2(cre)Rph>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal fetal cardiomyocyte morphology
  http://purl.obolibrary.org/obo/MP_0008788

文献

http://purl.org/net/cito/citesAsAuthority

• Jörg-Detlef. Drenckhahn, et.al., Compensatory growth of healthy cardiac cells in the presence of diseased cells restores tissue homeostasis during heart development., Developmental cell, 2008, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/18854137