increased liver iron level_Hfe<tm1.1Wsr>/Hfe<tm1.1Wsr>

http://metadb.riken.jp/0008807I129P2OlaHsdC57BL6Hfetm11WsrHfetm11WsrHfetm11Wsr

increased liver iron level_Hfe<tm1.1Wsr>/Hfe<tm1.1Wsr>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• hemochromatosis
  http://metadb.riken.jp/db/mgi_rdf/MGI:109191

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hfe<tm1.1Wsr>/Hfe<tm1.1Wsr>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hfe<tm1.1Wsr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased liver iron level
  http://purl.obolibrary.org/obo/MP_0008807

文献

http://purl.org/net/cito/citesAsAuthority

• Maja. Vujic Spasic, et.al., Physiologic systemic iron metabolism in mice deficient for duodenal Hfe., Blood, 2007, 109
  http://rdf.ncbi.nlm.nih.gov/pubmed/17264297
• Maja. Vujić Spasić, et.al., Hfe acts in hepatocytes to prevent hemochromatosis., Cell metabolism, 2008, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/18249176
• Thomas. Herrmann, et.al., Iron overload in adult Hfe-deficient mice independent of changes in the steady-state expression of the duodenal iron transporters DMT1 and Ireg1/ferroportin., Journal of molecular medicine (Berlin, Germany), 2004, 82
  http://rdf.ncbi.nlm.nih.gov/pubmed/14618243