lipofuscinosis_Lrrk2<tm2.1Shn>/Lrrk2<tm2.1Shn>

http://metadb.riken.jp/0008842I129C57BL6Lrrk2tm21ShnLrrk2tm21ShnLrrk2tm21Shn

lipofuscinosis_Lrrk2<tm2.1Shn>/Lrrk2<tm2.1Shn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• leucine-rich repeat kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1913975

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lrrk2<tm2.1Shn>/Lrrk2<tm2.1Shn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lrrk2<tm2.1Shn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• lipofuscinosis
  http://purl.obolibrary.org/obo/MP_0008842

文献

http://purl.org/net/cito/citesAsAuthority

• Youren. Tong, et.al., Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of alpha-synuclein, and apoptotic cell death in aged mice., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20457918