abnormal physiological response to xenobiotic_Cftr<tm1Eur>/Cftr<tm1Eur>,Slc9a3r1<tm1Ssl>/Slc9a3r1<tm1Ssl>

http://metadb.riken.jp/0008872I129P2OlaHsd129S1Sv129X1SvJCftrtm1EurCftrtm1EurSlc9a3r1tm1SslSlc9a3r1tm1SslCftrtm1EurSlc9a3r1tm1Ssl

abnormal physiological response to xenobiotic_Cftr<tm1Eur>/Cftr<tm1Eur>,Slc9a3r1<tm1Ssl>/Slc9a3r1<tm1Ssl>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cystic fibrosis transmembrane conductance regulator
  http://metadb.riken.jp/db/mgi_rdf/MGI:88388
• solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1349482

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cftr<tm1Eur>/Cftr<tm1Eur>,Slc9a3r1<tm1Ssl>/Slc9a3r1<tm1Ssl>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cftr<tm1Eur>|Slc9a3r1<tm1Ssl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal physiological response to xenobiotic
  http://purl.obolibrary.org/obo/MP_0008872

文献

http://purl.org/net/cito/citesAsAuthority

• Nellie. Broere, et.al., Cystic fibrosis transmembrane conductance regulator activation is reduced in the small intestine of Na+/H+ exchanger 3 regulatory factor 1 (NHERF-1)- but Not NHERF-2-deficient mice., The Journal of biological chemistry, 2007, 282
  http://rdf.ncbi.nlm.nih.gov/pubmed/17947234