abnormal physiological response to xenobiotic_Nfe2l2<tm1Mym>/Nfe2l2<tm1Mym>

http://metadb.riken.jp/0008872I129P2OlaHsdICRNfe2l2tm1MymNfe2l2tm1MymNfe2l2tm1Mym

abnormal physiological response to xenobiotic_Nfe2l2<tm1Mym>/Nfe2l2<tm1Mym>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• nuclear factor, erythroid derived 2, like 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:108420

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nfe2l2<tm1Mym>/Nfe2l2<tm1Mym>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nfe2l2<tm1Mym>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * ICR

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal physiological response to xenobiotic
  http://purl.obolibrary.org/obo/MP_0008872

文献

http://purl.org/net/cito/citesAsAuthority

• M. Ramos-Gomez, et.al., Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice., Proceedings of the National Academy of Sciences of the United States of America, 2001, 98
  http://rdf.ncbi.nlm.nih.gov/pubmed/11248092
• Hye-Youn. Cho, et.al., The transcription factor NRF2 protects against pulmonary fibrosis., FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, 18
  http://rdf.ncbi.nlm.nih.gov/pubmed/15208274