increased physiological sensitivity to xenobiotic_Ryr2<tm1.1Swch>/Ryr2<+>

http://metadb.riken.jp/0008873I129S1Sv129X1SvJBlackSwissRyr2tm11SwchRyr2Ryr2tm11SwchRyr2

increased physiological sensitivity to xenobiotic_Ryr2<tm1.1Swch>/Ryr2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ryanodine receptor 2, cardiac
  http://metadb.riken.jp/db/mgi_rdf/MGI:99685

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ryr2<tm1.1Swch>/Ryr2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ryr2<tm1.1Swch>|Ryr2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * Black Swiss

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased physiological sensitivity to xenobiotic
  http://purl.obolibrary.org/obo/MP_0008873

文献

http://purl.org/net/cito/citesAsAuthority

• Qiang. Zhou, et.al., Carvedilol and its new analogs suppress arrhythmogenic store overload-induced Ca2+ release., Nature medicine, 2011, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/21743453