increased physiological sensitivity to xenobiotic_Bche<tm1Loc>/Bche<+>

http://metadb.riken.jp/0008873I129S1SvBchetm1LocBcheBcheBchetm1Loc

increased physiological sensitivity to xenobiotic_Bche<tm1Loc>/Bche<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• butyrylcholinesterase
  http://metadb.riken.jp/db/mgi_rdf/MGI:894278

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bche<tm1Loc>/Bche<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Bche<+>|Bche<tm1Loc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased physiological sensitivity to xenobiotic
  http://purl.obolibrary.org/obo/MP_0008873

文献

http://purl.org/net/cito/citesAsAuthority

• Ellen G. Duysen, et.al., Sensitivity of butyrylcholinesterase knockout mice to (--)-huperzine A and donepezil suggests humans with butyrylcholinesterase deficiency may not tolerate these Alzheimer's disease drugs and indicates butyrylcholinesterase function in neurotransmission., Toxicology, 2007, 233
  http://rdf.ncbi.nlm.nih.gov/pubmed/17194517