increased physiological sensitivity to xenobiotic_Abcc1<tm1Acs>/Abcc1<tm1Acs>

http://metadb.riken.jp/0008873I129S1SvC57BL6Abcc1tm1AcsAbcc1tm1AcsAbcc1tm1Acs

increased physiological sensitivity to xenobiotic_Abcc1<tm1Acs>/Abcc1<tm1Acs>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:102676

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Abcc1<tm1Acs>/Abcc1<tm1Acs>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Abcc1<tm1Acs>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased physiological sensitivity to xenobiotic
  http://purl.obolibrary.org/obo/MP_0008873

文献

http://purl.org/net/cito/citesAsAuthority

• A. Lorico, et.al., Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione., Cancer research, 1997, 57
  http://rdf.ncbi.nlm.nih.gov/pubmed/9393741