increased physiological sensitivity to xenobiotic_Stat3<tm1Xyfu>/Stat3<tm1.1Xyfu>,Tg(Myh6-cre)2182Mds/0

http://metadb.riken.jp/0008873I129S1SvFVBNStat3tm1XyfuStat3tm11XyfuTgMyh6cre2182Mds0TgMyh6cre2182MdsStat3tm1XyfuStat3tm11Xyfu

increased physiological sensitivity to xenobiotic_Stat3<tm1Xyfu>/Stat3<tm1.1Xyfu>,Tg(Myh6-cre)2182Mds/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2182, Michael D Schneider
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447636
• signal transducer and activator of transcription 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:103038

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Stat3<tm1Xyfu>/Stat3<tm1.1Xyfu>,Tg(Myh6-cre)2182Mds/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Myh6-cre)2182Mds|Stat3<tm1Xyfu>|Stat3<tm1.1Xyfu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased physiological sensitivity to xenobiotic
  http://purl.obolibrary.org/obo/MP_0008873

文献

http://purl.org/net/cito/citesAsAuthority

• Jörg J. Jacoby, et.al., Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age., Proceedings of the National Academy of Sciences of the United States of America, 2003, 100
  http://rdf.ncbi.nlm.nih.gov/pubmed/14566054