increased physiological sensitivity to xenobiotic_Abcb1a<mds>/Abcb1a<mds>

http://metadb.riken.jp/0008873ICF1Abcb1amdsAbcb1amdsAbcb1amds

increased physiological sensitivity to xenobiotic_Abcb1a<mds>/Abcb1a<mds>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ATP-binding cassette, sub-family B (MDR/TAP), member 1A
  http://metadb.riken.jp/db/mgi_rdf/MGI:97570

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Abcb1a<mds>/Abcb1a<mds>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Abcb1a<mds>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: CF-1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased physiological sensitivity to xenobiotic
  http://purl.obolibrary.org/obo/MP_0008873

文献

http://purl.org/net/cito/citesAsAuthority

• G R. Lankas, et.al., P-glycoprotein deficiency in a subpopulation of CF-1 mice enhances avermectin-induced neurotoxicity., Toxicology and applied pharmacology, 1997, 143
  http://rdf.ncbi.nlm.nih.gov/pubmed/9144452
• K. Jun, et.al., Insertion of a retroviral solo long terminal repeat in mdr-3 locus disrupts mRNA splicing in mice., Mammalian genome : official journal of the International Mammalian Genome Society, 2000, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/11003697