decreased physiological sensitivity to xenobiotic_Cyp1a1<tm1.1Dwn>/Cyp1a1<tm1.1Dwn>

http://metadb.riken.jp/0008874B6129P2Cyp1a1tm11DwnCyp1a1tm11DwnCyp1a1tm11DwnCyp1a1tm11Dwn

decreased physiological sensitivity to xenobiotic_Cyp1a1<tm1.1Dwn>/Cyp1a1<tm1.1Dwn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cytochrome P450, family 1, subfamily a, polypeptide 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88588

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cyp1a1<tm1.1Dwn>/Cyp1a1<tm1.1Dwn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cyp1a1<tm1.1Dwn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.129P2-Cyp1a1<tm1.1Dwn>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased physiological sensitivity to xenobiotic
  http://purl.obolibrary.org/obo/MP_0008874

文献

http://purl.org/net/cito/citesAsAuthority

• Shigeyuki. Uno, et.al., Cyp1a1(-/-) male mice: protection against high-dose TCDD-induced lethality and wasting syndrome, and resistance to intrahepatocyte lipid accumulation and uroporphyria., Toxicology and applied pharmacology, 2004, 196
  http://rdf.ncbi.nlm.nih.gov/pubmed/15094312