decreased physiological sensitivity to xenobiotic_Keap1<tm1Mym>/Keap1<tm2Mym>,Tg(Alb-cre)21Mgn/?

http://metadb.riken.jp/0008874I129P2OlaHsdC57BL6DBAKeap1tm1MymKeap1tm2MymTgAlbcre21MgnKeap1tm2MymTgAlbcre21MgnKeap1tm1Mym

decreased physiological sensitivity to xenobiotic_Keap1<tm1Mym>/Keap1<tm2Mym>,Tg(Alb-cre)21Mgn/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226
• kelch-like ECH-associated protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1858732

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Keap1<tm1Mym>/Keap1<tm2Mym>,Tg(Alb-cre)21Mgn/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Keap1<tm2Mym>|Tg(Alb-cre)21Mgn|Keap1<tm1Mym>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased physiological sensitivity to xenobiotic
  http://purl.obolibrary.org/obo/MP_0008874

文献

http://purl.org/net/cito/citesAsAuthority

• Hiromi. Okawa, et.al., Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity., Biochemical and biophysical research communications, 2006, 339
  http://rdf.ncbi.nlm.nih.gov/pubmed/16293230