decreased physiological sensitivity to xenobiotic_Pde8a<tm1Dgen>/Pde8a<tm1Dgen>,Pde8b<tm1Dgen>/Pde8b<tm1Dgen>

http://metadb.riken.jp/0008874I129P2OlaHsdC57BL6Pde8atm1DgenPde8atm1DgenPde8btm1DgenPde8btm1DgenPde8btm1DgenPde8atm1Dgen

decreased physiological sensitivity to xenobiotic_Pde8a<tm1Dgen>/Pde8a<tm1Dgen>,Pde8b<tm1Dgen>/Pde8b<tm1Dgen>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphodiesterase 8B
  http://metadb.riken.jp/db/mgi_rdf/MGI:2443999
• phosphodiesterase 8A
  http://metadb.riken.jp/db/mgi_rdf/MGI:1277116

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pde8a<tm1Dgen>/Pde8a<tm1Dgen>,Pde8b<tm1Dgen>/Pde8b<tm1Dgen>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pde8b<tm1Dgen>|Pde8a<tm1Dgen>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased physiological sensitivity to xenobiotic
  http://purl.obolibrary.org/obo/MP_0008874

文献

http://purl.org/net/cito/citesAsAuthority

• Li-Chun Lisa. Tsai, et.al., The high-affinity cAMP-specific phosphodiesterase 8B controls steroidogenesis in the mouse adrenal gland., Molecular pharmacology, 2011, 79
  http://rdf.ncbi.nlm.nih.gov/pubmed/21187369