decreased physiological sensitivity to xenobiotic_Oprm1<tm1Lex>/Oprm1<tm1Lex>

http://metadb.riken.jp/0008874I129S5SvEvBrdC57BL6NTacOprm1tm1LexOprm1tm1LexOprm1tm1Lex

decreased physiological sensitivity to xenobiotic_Oprm1<tm1Lex>/Oprm1<tm1Lex>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• opioid receptor, mu 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97441

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Oprm1<tm1Lex>/Oprm1<tm1Lex>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Oprm1<tm1Lex>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S5/SvEvBrd * C57BL/6NTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased physiological sensitivity to xenobiotic
  http://purl.obolibrary.org/obo/MP_0008874

文献

http://purl.org/net/cito/citesAsAuthority

• Babette. Kögel, et.al., The antinociceptive and antihyperalgesic effect of tapentadol is partially retained in OPRM1 (μ-opioid receptor) knockout mice., Neuroscience letters, 2011, 491
  http://rdf.ncbi.nlm.nih.gov/pubmed/21232580