decreased physiological sensitivity to xenobiotic_Nr1i3<tm1Ddm>/Nr1i3<tm1Ddm>

http://metadb.riken.jp/0008874I129S7SvEvBrdC57BL6Nr1i3tm1DdmNr1i3tm1DdmNr1i3tm1Ddm

decreased physiological sensitivity to xenobiotic_Nr1i3<tm1Ddm>/Nr1i3<tm1Ddm>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• nuclear receptor subfamily 1, group I, member 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346307

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nr1i3<tm1Ddm>/Nr1i3<tm1Ddm>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nr1i3<tm1Ddm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased physiological sensitivity to xenobiotic
  http://purl.obolibrary.org/obo/MP_0008874

文献

http://purl.org/net/cito/citesAsAuthority

• Wendong. Huang, et.al., Induction of bilirubin clearance by the constitutive androstane receptor (CAR)., Proceedings of the National Academy of Sciences of the United States of America, 2003, 100
  http://rdf.ncbi.nlm.nih.gov/pubmed/12644704
• P. Wei, et.al., The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism., Nature, 2000, 407
  http://rdf.ncbi.nlm.nih.gov/pubmed/11057673
• Jun. Zhang, et.al., Modulation of acetaminophen-induced hepatotoxicity by the xenobiotic receptor CAR., Science (New York, N.Y.), 2002, 298
  http://rdf.ncbi.nlm.nih.gov/pubmed/12376703