decreased physiological sensitivity to xenobiotic_Kcna5<tm1(Kcna1)Lndn>/Kcna5<tm1(Kcna1)Lndn>

http://metadb.riken.jp/0008874IC57BL6Kcna5tm1Kcna1LndnKcna5tm1Kcna1LndnKcna5tm1Kcna1Lndn

decreased physiological sensitivity to xenobiotic_Kcna5<tm1(Kcna1)Lndn>/Kcna5<tm1(Kcna1)Lndn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• potassium voltage-gated channel, shaker-related subfamily, member 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:96662

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kcna5<tm1(Kcna1)Lndn>/Kcna5<tm1(Kcna1)Lndn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kcna5<tm1(Kcna1)Lndn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased physiological sensitivity to xenobiotic
  http://purl.obolibrary.org/obo/MP_0008874

文献

http://purl.org/net/cito/citesAsAuthority

• B. London, et.al., Targeted replacement of KV1.5 in the mouse leads to loss of the 4-aminopyridine-sensitive component of I(K,slow) and resistance to drug-induced qt prolongation., Circulation research, 2001, 88
  http://rdf.ncbi.nlm.nih.gov/pubmed/11349004