abnormal xenobiotic pharmacokinetics_Comt<tm1Mkae>/Comt<tm1Mkae>

http://metadb.riken.jp/0008875IC57BL6JComttm1MkaeComttm1MkaeComttm1Mkae

abnormal xenobiotic pharmacokinetics_Comt<tm1Mkae>/Comt<tm1Mkae>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• catechol-O-methyltransferase
  http://metadb.riken.jp/db/mgi_rdf/MGI:88470

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Comt<tm1Mkae>/Comt<tm1Mkae>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Comt<tm1Mkae>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal xenobiotic pharmacokinetics
  http://purl.obolibrary.org/obo/MP_0008875

文献

http://purl.org/net/cito/citesAsAuthority

• M. Käenmäki, et.al., Importance of membrane-bound catechol-O-methyltransferase in L-DOPA metabolism: a pharmacokinetic study in two types of Comt gene modified mice., British journal of pharmacology, 2009, 158
  http://rdf.ncbi.nlm.nih.gov/pubmed/19930170