abnormal enterocyte proliferation_Gt(ROSA)26Sor<tm2(Rnf187)Jhai>/Gt(ROSA)26Sor<+>,Kras<tm4Tyj>/Kras<+>,Tg(Vil-cre)20Syr/0

http://metadb.riken.jp/0008883I129S4SvJae129S6SvEvTacC57BL6DBA2GtROSA26Sortm2Rnf187JhaiGtROSA26SorKrastm4TyjKrasTgVilcre20Syr0GtROSA26Sortm2Rnf187JhaiGtROSA26SorTgVilcre20SyrKrasKrastm4Tyj

abnormal enterocyte proliferation_Gt(ROSA)26Sor<tm2(Rnf187)Jhai>/Gt(ROSA)26Sor<+>,Kras<tm4Tyj>/Kras<+>,Tg(Vil-cre)20Syr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 20, Sylvie Robine
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053809
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm2(Rnf187)Jhai>/Gt(ROSA)26Sor<+>,Kras<tm4Tyj>/Kras<+>,Tg(Vil-cre)20Syr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm2(Rnf187)Jhai>|Gt(ROSA)26Sor<+>|Tg(Vil-cre)20Syr|Kras<+>|Kras<tm4Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal enterocyte proliferation
  http://purl.obolibrary.org/obo/MP_0008883

文献

http://purl.org/net/cito/citesAsAuthority

• Clare C. Davies, et.al., Identification of a co-activator that links growth factor signalling to c-Jun/AP-1 activation., Nature cell biology, 2010, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/20852630