microgliosis_Psmc4<tm1.1Ryot>/Psmc4<tm1.2Ryot>,Tg(SLC18A3-cre)KMisa/0

http://metadb.riken.jp/0008918IC57BL6C57BL6NPsmc4tm11RyotPsmc4tm12RyotTgSLC18A3creKMisa0Psmc4tm12RyotTgSLC18A3creKMisaPsmc4tm11Ryot

microgliosis_Psmc4<tm1.1Ryot>/Psmc4<tm1.2Ryot>,Tg(SLC18A3-cre)KMisa/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• proteasome (prosome, macropain) 26S subunit, ATPase, 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346093
• transgene insertion K, Hidemi Misawa
  http://metadb.riken.jp/db/mgi_rdf/MGI:2679340

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Psmc4<tm1.1Ryot>/Psmc4<tm1.2Ryot>,Tg(SLC18A3-cre)KMisa/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Psmc4<tm1.2Ryot>|Tg(SLC18A3-cre)KMisa|Psmc4<tm1.1Ryot>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * C57BL/6N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• microgliosis
  http://purl.obolibrary.org/obo/MP_0008918

文献

http://purl.org/net/cito/citesAsAuthority

• Yoshitaka. Tashiro, et.al., Motor neuron-specific disruption of proteasomes, but not autophagy, replicates amyotrophic lateral sclerosis., The Journal of biological chemistry, 2012, 287
  http://rdf.ncbi.nlm.nih.gov/pubmed/23095749