increased sensitivity to induced cell death_Pink1<tm1Hlw>/Pink1<tm1Hlw>

http://metadb.riken.jp/0008943I129C57BL6JPink1tm1HlwPink1tm1HlwPink1tm1Hlw

increased sensitivity to induced cell death_Pink1<tm1Hlw>/Pink1<tm1Hlw>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• PTEN induced putative kinase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1916193

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pink1<tm1Hlw>/Pink1<tm1Hlw>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pink1<tm1Hlw>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased sensitivity to induced cell death
  http://purl.obolibrary.org/obo/MP_0008943

文献

http://purl.org/net/cito/citesAsAuthority

• Hung-Li. Wang, et.al., PARK6 PINK1 mutants are defective in maintaining mitochondrial membrane potential and inhibiting ROS formation of substantia nigra dopaminergic neurons., Biochimica et biophysica acta, 2011, 1812
  http://rdf.ncbi.nlm.nih.gov/pubmed/21421046