increased sensitivity to induced cell death_Esyt2<Gt(AN0678)Wtsi>/Esyt2<Gt(AN0678)Wtsi>,Esyt3<tm1d(EUCOMM)Wtsi>/Esyt3<tm1d(EUCOMM)Wtsi>

http://metadb.riken.jp/0008943I129P2OlaHsdC57BL6NEsyt2GtAN0678WtsiEsyt2GtAN0678WtsiEsyt3tm1dEUCOMMWtsiEsyt3tm1dEUCOMMWtsiEsyt2GtAN0678WtsiEsyt3tm1dEUCOMMWtsi

increased sensitivity to induced cell death_Esyt2<Gt(AN0678)Wtsi>/Esyt2<Gt(AN0678)Wtsi>,Esyt3<tm1d(EUCOMM)Wtsi>/Esyt3<tm1d(EUCOMM)Wtsi>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• extended synaptotagmin-like protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1261845
• extended synaptotagmin-like protein 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1098699

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Esyt2<Gt(AN0678)Wtsi>/Esyt2<Gt(AN0678)Wtsi>,Esyt3<tm1d(EUCOMM)Wtsi>/Esyt3<tm1d(EUCOMM)Wtsi>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Esyt2<Gt(AN0678)Wtsi>|Esyt3<tm1d(EUCOMM)Wtsi>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased sensitivity to induced cell death
  http://purl.obolibrary.org/obo/MP_0008943

文献

http://purl.org/net/cito/citesAsAuthority

• Chelsea. Herdman, et.al., Loss of Extended Synaptotagmins ESyt2 and ESyt3 does not affect mouse development or viability, but in vitro cell migration and survival under stress are affected., Cell cycle (Georgetown, Tex.), 2014, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/25486202