increased sensitivity to induced cell death_Appl1<tm1.2Test>/Appl1<tm1.2Test>

http://metadb.riken.jp/0008943I129X1SvJC57BL6Appl1tm12TestAppl1tm12TestAppl1tm12Test

increased sensitivity to induced cell death_Appl1<tm1.2Test>/Appl1<tm1.2Test>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1920243

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Appl1<tm1.2Test>/Appl1<tm1.2Test>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Appl1<tm1.2Test>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased sensitivity to induced cell death
  http://purl.obolibrary.org/obo/MP_0008943

文献

http://purl.org/net/cito/citesAsAuthority

• Yinfei. Tan, et.al., Appl1 is dispensable for mouse development, and loss of Appl1 has growth factor-selective effects on Akt signaling in murine embryonic fibroblasts., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20040596