decreased neuron number_Wnt1<tm1.1Mze>/Wnt1<tm1.1Mze>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>,En1<tm2(cre)Wrst>/En1<+>

http://metadb.riken.jp/0008948I129C57BL6NWnt1tm11MzeWnt1tm11MzeGtROSA26Sortm14CAGtdTomatoHzeGtROSA26SorEn1tm2creWrstEn1GtROSA26SorWnt1tm11MzeGtROSA26Sortm14CAGtdTomatoHzeEn1tm2creWrstEn1

decreased neuron number_Wnt1<tm1.1Mze>/Wnt1<tm1.1Mze>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>,En1<tm2(cre)Wrst>/En1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• wingless-type MMTV integration site family, member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:98953
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• engrailed 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95389

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Wnt1<tm1.1Mze>/Wnt1<tm1.1Mze>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>,En1<tm2(cre)Wrst>/En1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<+>|Wnt1<tm1.1Mze>|Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>|En1<tm2(cre)Wrst>|En1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased neuron number
  http://purl.obolibrary.org/obo/MP_0008948

文献

http://purl.org/net/cito/citesAsAuthority

• Jasmine. Yang, et.al., Dynamic temporal requirement of Wnt1 in midbrain dopamine neuron development., Development (Cambridge, England), 2013, 140
  http://rdf.ncbi.nlm.nih.gov/pubmed/23444360