decreased erythroid progenitor cell number_Bcl2l11<tm1.1Ast>/Bcl2l11<tm1.1Ast>,Gata1<tm1.1Yen>/Gata1<tm1.1Yen>

http://metadb.riken.jp/0008973I129S1Sv129X1SvJC57BL6FVBNBcl2l11tm11AstBcl2l11tm11AstGata1tm11YenGata1tm11YenGata1tm11YenBcl2l11tm11Ast

decreased erythroid progenitor cell number_Bcl2l11<tm1.1Ast>/Bcl2l11<tm1.1Ast>,Gata1<tm1.1Yen>/Gata1<tm1.1Yen>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• GATA binding protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95661
• BCL2-like 11 (apoptosis facilitator)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1197519

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bcl2l11<tm1.1Ast>/Bcl2l11<tm1.1Ast>,Gata1<tm1.1Yen>/Gata1<tm1.1Yen>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gata1<tm1.1Yen>|Bcl2l11<tm1.1Ast>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased erythroid progenitor cell number
  http://purl.obolibrary.org/obo/MP_0008973

文献

http://purl.org/net/cito/citesAsAuthority

• Kou-Ray. Lin, et.al., Constitutive phosphorylation of GATA-1 at serine²⁶ attenuates the colony-forming activity of erythrocyte-committed progenitors., PloS one, 2013, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/23717580