abnormal bile canaliculus morphology_Chuk<tm1Mpa>/Chuk<tm1Mpa>,Ikbkb<tm2Cgn>/Ikbkb<tm2Cgn>,Tg(Alb1-cre)7Gsc/0

http://metadb.riken.jp/0008991IC57BL6FVBNChuktm1MpaChuktm1MpaIkbkbtm2CgnIkbkbtm2CgnTgAlb1cre7Gsc0Chuktm1MpaIkbkbtm2CgnTgAlb1cre7Gsc

abnormal bile canaliculus morphology_Chuk<tm1Mpa>/Chuk<tm1Mpa>,Ikbkb<tm2Cgn>/Ikbkb<tm2Cgn>,Tg(Alb1-cre)7Gsc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 7, Gunther Schutz
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177601
• inhibitor of kappaB kinase beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:1338071
• conserved helix-loop-helix ubiquitous kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:99484

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Chuk<tm1Mpa>/Chuk<tm1Mpa>,Ikbkb<tm2Cgn>/Ikbkb<tm2Cgn>,Tg(Alb1-cre)7Gsc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Chuk<tm1Mpa>|Ikbkb<tm2Cgn>|Tg(Alb1-cre)7Gsc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal bile canaliculus morphology
  http://purl.obolibrary.org/obo/MP_0008991

文献

http://purl.org/net/cito/citesAsAuthority

• Tom. Luedde, et.al., IKK1 and IKK2 cooperate to maintain bile duct integrity in the liver., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105
  http://rdf.ncbi.nlm.nih.gov/pubmed/18606991