increased pancreatic beta cell mass_Lepr<db>/Lepr<+>,Tg(APPswe,PSEN1dE9)85Dbo/0

http://metadb.riken.jp/0009113IC3HC57BL6C57BLKSJLeprdbLeprTgAPPswePSEN1dE985Dbo0LeprdbLeprTgAPPswePSEN1dE985Dbo

increased pancreatic beta cell mass_Lepr<db>/Lepr<+>,Tg(APPswe,PSEN1dE9)85Dbo/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 85, David R Borchelt
  http://metadb.riken.jp/db/mgi_rdf/MGI:3525178
• leptin receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:104993

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lepr<db>/Lepr<+>,Tg(APPswe,PSEN1dE9)85Dbo/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lepr<db>|Lepr<+>|Tg(APPswe,PSEN1dE9)85Dbo

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C3H * C57BL/6 * C57BLKS/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pancreatic beta cell mass
  http://purl.obolibrary.org/obo/MP_0009113

文献

http://purl.org/net/cito/citesAsAuthority

• Margarita. Jiménez-Palomares, et.al., Increased Aβ production prompts the onset of glucose intolerance and insulin resistance., American journal of physiology. Endocrinology and metabolism, 2012, 302
  http://rdf.ncbi.nlm.nih.gov/pubmed/22414803