decreased pancreatic beta cell mass_Gsk3b<tm1Jrw>/Gsk3b<+>,Insr<tm1Dac>/Insr<+>

http://metadb.riken.jp/0009114I129C57BL6JGsk3btm1JrwGsk3bInsrtm1DacInsrGsk3btm1JrwInsrtm1DacInsrGsk3b

decreased pancreatic beta cell mass_Gsk3b<tm1Jrw>/Gsk3b<+>,Insr<tm1Dac>/Insr<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• glycogen synthase kinase 3 beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:1861437
• insulin receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96575

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gsk3b<tm1Jrw>/Gsk3b<+>,Insr<tm1Dac>/Insr<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gsk3b<tm1Jrw>|Insr<tm1Dac>|Insr<+>|Gsk3b<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased pancreatic beta cell mass
  http://purl.obolibrary.org/obo/MP_0009114

文献

http://purl.org/net/cito/citesAsAuthority

• Katsuya. Tanabe, et.al., Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance., PLoS biology, 2008, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/18288891