decreased pancreatic beta cell mass_Tcf7l2<tm1Geno>/Tcf7l2<tm1Geno>,Tg(Pdx1-cre)89.1Dam/0

http://metadb.riken.jp/0009114IC57BL6CBATcf7l2tm1GenoTcf7l2tm1GenoTgPdx1cre891Dam0TgPdx1cre891DamTcf7l2tm1Geno

decreased pancreatic beta cell mass_Tcf7l2<tm1Geno>/Tcf7l2<tm1Geno>,Tg(Pdx1-cre)89.1Dam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 89.1, Douglas A Melton
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684318
• transcription factor 7 like 2, T cell specific, HMG box
  http://metadb.riken.jp/db/mgi_rdf/MGI:1202879

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tcf7l2<tm1Geno>/Tcf7l2<tm1Geno>,Tg(Pdx1-cre)89.1Dam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Pdx1-cre)89.1Dam|Tcf7l2<tm1Geno>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased pancreatic beta cell mass
  http://purl.obolibrary.org/obo/MP_0009114

文献

http://purl.org/net/cito/citesAsAuthority

• G. da Silva Xavier, et.al., Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice., Diabetologia, 2012, 55
  http://rdf.ncbi.nlm.nih.gov/pubmed/22717537