increased pancreatic ductal adenocarcinoma incidence_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pdx1-cre)89.1Dam/0,Trp53<tm1Tyj>/Trp53<tm1Tyj>

http://metadb.riken.jp/0009151I129S2SvPas129S4SvJaeC57BL6CBAPtentm1HwuPtentm1HwuTgPdx1cre891Dam0Trp53tm1TyjTrp53tm1TyjTrp53tm1TyjPtentm1HwuTgPdx1cre891Dam

increased pancreatic ductal adenocarcinoma incidence_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pdx1-cre)89.1Dam/0,Trp53<tm1Tyj>/Trp53<tm1Tyj>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 89.1, Douglas A Melton
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684318
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pdx1-cre)89.1Dam/0,Trp53<tm1Tyj>/Trp53<tm1Tyj>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Tyj>|Pten<tm1Hwu>|Tg(Pdx1-cre)89.1Dam

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pancreatic ductal adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0009151

文献

http://purl.org/net/cito/citesAsAuthority

• Ben Z. Stanger, et.al., Pten constrains centroacinar cell expansion and malignant transformation in the pancreas., Cancer cell, 2005, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/16169464