increased pancreatic intraepithelial neoplasia incidence_Kras<tm4Tyj>/Kras<tm4Tyj>,Bhlha15<tm3(cre/ERT2)Skz>/Bhlha15<+>

http://metadb.riken.jp/0009152I129S1Sv129S4SvJae129X1SvJKrastm4TyjKrastm4TyjBhlha15tm3creERT2SkzBhlha15Krastm4TyjBhlha15tm3creERT2SkzBhlha15

increased pancreatic intraepithelial neoplasia incidence_Kras<tm4Tyj>/Kras<tm4Tyj>,Bhlha15<tm3(cre/ERT2)Skz>/Bhlha15<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• basic helix-loop-helix family, member a15
  http://metadb.riken.jp/db/mgi_rdf/MGI:891976

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<tm4Tyj>,Bhlha15<tm3(cre/ERT2)Skz>/Bhlha15<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kras<tm4Tyj>|Bhlha15<tm3(cre/ERT2)Skz>|Bhlha15<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pancreatic intraepithelial neoplasia incidence
  http://purl.obolibrary.org/obo/MP_0009152

文献

http://purl.org/net/cito/citesAsAuthority

• Nils. Habbe, et.al., Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105
  http://rdf.ncbi.nlm.nih.gov/pubmed/19028870