increased pancreatic intraepithelial neoplasia incidence_Kras<tm4Tyj>/Kras<tm4Tyj>,Tg(Pdx1-cre/Esr1*)35.10Dam/0

http://metadb.riken.jp/0009152I129S4SvJaeC57BL6CBAKrastm4TyjKrastm4TyjTgPdx1creEsr13510Dam0Krastm4TyjTgPdx1creEsr13510Dam

increased pancreatic intraepithelial neoplasia incidence_Kras<tm4Tyj>/Kras<tm4Tyj>,Tg(Pdx1-cre/Esr1*)35.10Dam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 35.10, Douglas A Melton
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684322
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<tm4Tyj>,Tg(Pdx1-cre/Esr1*)35.10Dam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kras<tm4Tyj>|Tg(Pdx1-cre/Esr1*)35.10Dam

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pancreatic intraepithelial neoplasia incidence
  http://purl.obolibrary.org/obo/MP_0009152

文献

http://purl.org/net/cito/citesAsAuthority

• Jean-Paul. De La O, et.al., Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105
  http://rdf.ncbi.nlm.nih.gov/pubmed/19028876