increased pancreas tumor incidence_Cdkn2a<tm4Rdp>/Cdkn2a<tm4Rdp>,Kras<tm4Tyj>/Kras<tm4Tyj>,Tg(Pdx1-cre)89.1Dam/0

http://metadb.riken.jp/0009153I129S4SvJaeC57BL6DBA2Cdkn2atm4RdpCdkn2atm4RdpKrastm4TyjKrastm4TyjTgPdx1cre891Dam0TgPdx1cre891DamKrastm4TyjCdkn2atm4Rdp

increased pancreas tumor incidence_Cdkn2a<tm4Rdp>/Cdkn2a<tm4Rdp>,Kras<tm4Tyj>/Kras<tm4Tyj>,Tg(Pdx1-cre)89.1Dam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738
• transgene insertion 89.1, Douglas A Melton
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684318

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm4Rdp>/Cdkn2a<tm4Rdp>,Kras<tm4Tyj>/Kras<tm4Tyj>,Tg(Pdx1-cre)89.1Dam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Pdx1-cre)89.1Dam|Kras<tm4Tyj>|Cdkn2a<tm4Rdp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pancreas tumor incidence
  http://purl.obolibrary.org/obo/MP_0009153

文献

http://purl.org/net/cito/citesAsAuthority

• David F. Vincent, et.al., Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas., PLoS genetics, 2009, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/19629168