increased pancreas tumor incidence_Bcl2l1<tm1.1Mam>/Bcl2l1<tm1.1Mam>,Tg(Ins2-cre)25Mgn/0,Tg(RIP1-Tag)2Dh/0

http://metadb.riken.jp/0009153I129S6SvEvTacC57BL6DBABcl2l1tm11MamBcl2l1tm11MamTgIns2cre25Mgn0TgRIP1Tag2Dh0TgRIP1Tag2DhTgIns2cre25MgnBcl2l1tm11Mam

increased pancreas tumor incidence_Bcl2l1<tm1.1Mam>/Bcl2l1<tm1.1Mam>,Tg(Ins2-cre)25Mgn/0,Tg(RIP1-Tag)2Dh/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 25, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176225
• BCL2-like 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88139
• transgene insertion 2, Douglas Hanahan
  http://metadb.riken.jp/db/mgi_rdf/MGI:2429940

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bcl2l1<tm1.1Mam>/Bcl2l1<tm1.1Mam>,Tg(Ins2-cre)25Mgn/0,Tg(RIP1-Tag)2Dh/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(RIP1-Tag)2Dh|Tg(Ins2-cre)25Mgn|Bcl2l1<tm1.1Mam>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pancreas tumor incidence
  http://purl.obolibrary.org/obo/MP_0009153

文献

http://purl.org/net/cito/citesAsAuthority

• Jeffrey H. Hager, et.al., Genetic ablation of Bcl-x attenuates invasiveness without affecting apoptosis or tumor growth in a mouse model of pancreatic neuroendocrine cancer., PloS one, 2009, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/19209227