increased pancreas tumor incidence_Cdkn2a<tm1Rdp>/Cdkn2a<+>,Tg(CAG-Bgeo,-tTA,-EGFP)2A11Kuw/0,Tg(Pdx1-cre)6Tuv/0,Tg(tetO-MYC)36Bop/0

http://metadb.riken.jp/0009153I129Sv129P2OlaHsdC57BL6JFVBNSJLCdkn2atm1RdpCdkn2aTgCAGBgeotTAEGFP2A11Kuw0TgPdx1cre6Tuv0TgtetOMYC36Bop0Cdkn2atm1RdpCdkn2aTgPdx1cre6TuvTgtetOMYC36BopTgCAGBgeotTAEGFP2A11Kuw

increased pancreas tumor incidence_Cdkn2a<tm1Rdp>/Cdkn2a<+>,Tg(CAG-Bgeo,-tTA,-EGFP)2A11Kuw/0,Tg(Pdx1-cre)6Tuv/0,Tg(tetO-MYC)36Bop/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 6, David A Tuveson
  http://metadb.riken.jp/db/mgi_rdf/MGI:5437123
• transgene insertion 2A11, Kay-Uwe Wagner
  http://metadb.riken.jp/db/mgi_rdf/MGI:3849830
• transgene insertion 36, J Michael Bishop
  http://metadb.riken.jp/db/mgi_rdf/MGI:3039698
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm1Rdp>/Cdkn2a<+>,Tg(CAG-Bgeo,-tTA,-EGFP)2A11Kuw/0,Tg(Pdx1-cre)6Tuv/0,Tg(tetO-MYC)36Bop/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn2a<tm1Rdp>|Cdkn2a<+>|Tg(Pdx1-cre)6Tuv|Tg(tetO-MYC)36Bop|Tg(CAG-Bgeo,-tTA,-EGFP)2A11Kuw

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pancreas tumor incidence
  http://purl.obolibrary.org/obo/MP_0009153

文献

http://purl.org/net/cito/citesAsAuthority

• Wan-chi. Lin, et.al., Dormant cancer cells contribute to residual disease in a model of reversible pancreatic cancer., Cancer research, 2013, 73
  http://rdf.ncbi.nlm.nih.gov/pubmed/23467612