increased prostate intraepithelial neoplasia incidence_Hspa5<tm1Alee>/Hspa5<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pbsn-cre)4Prb/?

http://metadb.riken.jp/0009219I129129S4SvJaeC57BL6DBA2Hspa5tm1AleeHspa5Ptentm1HwuPtentm1HwuTgPbsncre4PrbTgPbsncre4PrbHspa5tm1AleePtentm1HwuHspa5

increased prostate intraepithelial neoplasia incidence_Hspa5<tm1Alee>/Hspa5<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pbsn-cre)4Prb/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• transgene insertion 4, Pradip Roy-Burman
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388169
• heat shock protein 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:95835

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hspa5<tm1Alee>/Hspa5<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pbsn-cre)4Prb/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Pbsn-cre)4Prb|Hspa5<tm1Alee>|Pten<tm1Hwu>|Hspa5<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129S4/SvJae * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased prostate intraepithelial neoplasia incidence
  http://purl.obolibrary.org/obo/MP_0009219

文献

http://purl.org/net/cito/citesAsAuthority

• Yong. Fu, et.al., Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105
  http://rdf.ncbi.nlm.nih.gov/pubmed/19033462