increased prostate intraepithelial neoplasia incidence_Brca2<tm1Brn>/Brca2<tm1Brn>,Trp53<tm1Brn>/Trp53<+>,Tg(Pbsn-cre)4Prb/0

http://metadb.riken.jp/0009219I129P2OlaHsdC57BL6DBA2Brca2tm1BrnBrca2tm1BrnTrp53tm1BrnTrp53TgPbsncre4Prb0TgPbsncre4PrbTrp53tm1BrnBrca2tm1BrnTrp53

increased prostate intraepithelial neoplasia incidence_Brca2<tm1Brn>/Brca2<tm1Brn>,Trp53<tm1Brn>/Trp53<+>,Tg(Pbsn-cre)4Prb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 4, Pradip Roy-Burman
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388169
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• breast cancer 2, early onset
  http://metadb.riken.jp/db/mgi_rdf/MGI:109337

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Brca2<tm1Brn>/Brca2<tm1Brn>,Trp53<tm1Brn>/Trp53<+>,Tg(Pbsn-cre)4Prb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Pbsn-cre)4Prb|Trp53<tm1Brn>|Brca2<tm1Brn>|Trp53<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased prostate intraepithelial neoplasia incidence
  http://purl.obolibrary.org/obo/MP_0009219

文献

http://purl.org/net/cito/citesAsAuthority

• Jeffrey C. Francis, et.al., Brca2 and Trp53 deficiency cooperate in the progression of mouse prostate tumourigenesis., PLoS genetics, 2010, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/20585617