increased prostate intraepithelial neoplasia incidence_Nkx3-1<tm1Mms>/Nkx3-1<tm1Mms>,Pten<tm1Rps>/Pten<+>

http://metadb.riken.jp/0009219I129S1Sv129S1SvImJC57BL6JNkx31tm1MmsNkx31tm1MmsPtentm1RpsPtenNkx31tm1MmsPtenPtentm1Rps

increased prostate intraepithelial neoplasia incidence_Nkx3-1<tm1Mms>/Nkx3-1<tm1Mms>,Pten<tm1Rps>/Pten<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• NK-3 transcription factor, locus 1 (Drosophila)
  http://metadb.riken.jp/db/mgi_rdf/MGI:97352

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nkx3-1<tm1Mms>/Nkx3-1<tm1Mms>,Pten<tm1Rps>/Pten<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nkx3-1<tm1Mms>|Pten<+>|Pten<tm1Rps>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S1/SvImJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased prostate intraepithelial neoplasia incidence
  http://purl.obolibrary.org/obo/MP_0009219

文献

http://purl.org/net/cito/citesAsAuthority

• Minjung J. Kim, et.al., Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis., Proceedings of the National Academy of Sciences of the United States of America, 2002, 99
  http://rdf.ncbi.nlm.nih.gov/pubmed/11854455