increased prostate intraepithelial neoplasia incidence_Kras<tm4Tyj>/Kras<+>,Scrib<tm1.1Phum>/Scrib<tm1.1Phum>,Tg(Pbsn-cre)20Fwan/0

http://metadb.riken.jp/0009219I129S4SvJaeFVBNCrlKrastm4TyjKrasScribtm11PhumScribtm11PhumTgPbsncre20Fwan0KrasKrastm4TyjScribtm11PhumTgPbsncre20Fwan

increased prostate intraepithelial neoplasia incidence_Kras<tm4Tyj>/Kras<+>,Scrib<tm1.1Phum>/Scrib<tm1.1Phum>,Tg(Pbsn-cre)20Fwan/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• scribbled planar cell polarity
  http://metadb.riken.jp/db/mgi_rdf/MGI:2145950
• transgene insertion 20, Fen Wang
  http://metadb.riken.jp/db/mgi_rdf/MGI:3717411

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Scrib<tm1.1Phum>/Scrib<tm1.1Phum>,Tg(Pbsn-cre)20Fwan/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kras<+>|Kras<tm4Tyj>|Scrib<tm1.1Phum>|Tg(Pbsn-cre)20Fwan

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * FVB/NCrl

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased prostate intraepithelial neoplasia incidence
  http://purl.obolibrary.org/obo/MP_0009219

文献

http://purl.org/net/cito/citesAsAuthority

• Helen B. Pearson, et.al., SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia., The Journal of clinical investigation, 2011, 121
  http://rdf.ncbi.nlm.nih.gov/pubmed/21965329