increased prostate intraepithelial neoplasia incidence_Ctnnb1<tm1Mmt>/Ctnnb1<+>,Tg(Pbsn-cre)4Prb/0

http://metadb.riken.jp/0009219I129X1SvJC57BL6DBA2Ctnnb1tm1MmtCtnnb1TgPbsncre4Prb0Ctnnb1Ctnnb1tm1MmtTgPbsncre4Prb

increased prostate intraepithelial neoplasia incidence_Ctnnb1<tm1Mmt>/Ctnnb1<+>,Tg(Pbsn-cre)4Prb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• catenin (cadherin associated protein), beta 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88276
• transgene insertion 4, Pradip Roy-Burman
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388169

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ctnnb1<tm1Mmt>/Ctnnb1<+>,Tg(Pbsn-cre)4Prb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ctnnb1<+>|Ctnnb1<tm1Mmt>|Tg(Pbsn-cre)4Prb

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased prostate intraepithelial neoplasia incidence
  http://purl.obolibrary.org/obo/MP_0009219

文献

http://purl.org/net/cito/citesAsAuthority

• Helen B. Pearson, et.al., K-ras and Wnt signaling synergize to accelerate prostate tumorigenesis in the mouse., Cancer research, 2009, 69
  http://rdf.ncbi.nlm.nih.gov/pubmed/19117991