increased prostate gland adenocarcinoma incidence_Ar<tm1Verh>/Y,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pbsn-cre)4Prb/0

http://metadb.riken.jp/0009220I129S1Sv129S4SvJae129X1SvJC57BL6DBA2Artm1VerhYPtentm1HwuPtentm1HwuTgPbsncre4Prb0Ptentm1HwuArtm1VerhTgPbsncre4Prb

increased prostate gland adenocarcinoma incidence_Ar<tm1Verh>/Y,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pbsn-cre)4Prb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• androgen receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:88064
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• transgene insertion 4, Pradip Roy-Burman
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388169

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ar<tm1Verh>/Y,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pbsn-cre)4Prb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pten<tm1Hwu>|Ar<tm1Verh>|Tg(Pbsn-cre)4Prb

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased prostate gland adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0009220

文献

http://purl.org/net/cito/citesAsAuthority

• David J. Mulholland, et.al., Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth., Cancer cell, 2011, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/21620777