increased prostate gland adenocarcinoma incidence_Pten<tm1Hwu>/Pten<+>,Tg(ARR2/Pbsn-FGF8)3Prb/0,Tg(Pbsn-cre)4Prb/0

http://metadb.riken.jp/0009220I129S4SvJaeBALBcC57BL6DBA2Ptentm1HwuPtenTgARR2PbsnFGF83Prb0TgPbsncre4Prb0TgPbsncre4PrbTgARR2PbsnFGF83PrbPtenPtentm1Hwu

increased prostate gland adenocarcinoma incidence_Pten<tm1Hwu>/Pten<+>,Tg(ARR2/Pbsn-FGF8)3Prb/0,Tg(Pbsn-cre)4Prb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 3, Pradip Roy-Burman
  http://metadb.riken.jp/db/mgi_rdf/MGI:2681438
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• transgene insertion 4, Pradip Roy-Burman
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388169

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1Hwu>/Pten<+>,Tg(ARR2/Pbsn-FGF8)3Prb/0,Tg(Pbsn-cre)4Prb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Pbsn-cre)4Prb|Tg(ARR2/Pbsn-FGF8)3Prb|Pten<+>|Pten<tm1Hwu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * BALB/c * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased prostate gland adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0009220

文献

http://purl.org/net/cito/citesAsAuthority

• Chen. Zhong, et.al., Cooperation between FGF8b overexpression and PTEN deficiency in prostate tumorigenesis., Cancer research, 2006, 66
  http://rdf.ncbi.nlm.nih.gov/pubmed/16489020