increased prostate gland adenocarcinoma incidence_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pbsn-cre)20Fwan/?

http://metadb.riken.jp/0009220I129S4SvJaeC57BL6FVBNCrlPtentm1HwuPtentm1HwuTgPbsncre20FwanPtentm1HwuTgPbsncre20Fwan

increased prostate gland adenocarcinoma incidence_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pbsn-cre)20Fwan/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• transgene insertion 20, Fen Wang
  http://metadb.riken.jp/db/mgi_rdf/MGI:3717411

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pbsn-cre)20Fwan/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pten<tm1Hwu>|Tg(Pbsn-cre)20Fwan

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * FVB/NCrl

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased prostate gland adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0009220

文献

http://purl.org/net/cito/citesAsAuthority

• Q. Su, et.al., Jagged1 upregulation in prostate epithelial cells promotes formation of reactive stroma in the Pten null mouse model for prostate cancer., Oncogene, 2017, 36
  http://rdf.ncbi.nlm.nih.gov/pubmed/27345403