increased prostate gland adenocarcinoma incidence_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(tetO-BRAF*V600E)29Lc/0,Tg(Tyr-rtTA)37Lc/0

http://metadb.riken.jp/0009220I129SvC57BL6JSJLCdkn2atm1RdpCdkn2atm1RdpTgtetOBRAFV600E29Lc0TgTyrrtTA37Lc0Cdkn2atm1RdpTgTyrrtTA37LcTgtetOBRAFV600E29Lc

increased prostate gland adenocarcinoma incidence_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(tetO-BRAF*V600E)29Lc/0,Tg(Tyr-rtTA)37Lc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 37, Lynda Chin
  http://metadb.riken.jp/db/mgi_rdf/MGI:3039789
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738
• transgene insertion 29, Lynda Chin
  http://metadb.riken.jp/db/mgi_rdf/MGI:3834719

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(tetO-BRAF*V600E)29Lc/0,Tg(Tyr-rtTA)37Lc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn2a<tm1Rdp>|Tg(Tyr-rtTA)37Lc|Tg(tetO-BRAF*V600E)29Lc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased prostate gland adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0009220

文献

http://purl.org/net/cito/citesAsAuthority

• Joseph H. Jeong, et.al., BRAF activation initiates but does not maintain invasive prostate adenocarcinoma., PloS one, 2008, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/19079609