increased prostate gland adenocarcinoma incidence_Tg(H-2K1-Lrp5/Fkbp1a,-luc*)#Dmps/0

http://metadb.riken.jp/0009220IFVBNTgH2K1Lrp5Fkbp1alucDmps0TgH2K1Lrp5Fkbp1alucDmps

increased prostate gland adenocarcinoma incidence_Tg(H-2K1-Lrp5/Fkbp1a,-luc*)#Dmps/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion, David M Spencer
  http://metadb.riken.jp/db/mgi_rdf/MGI:5633959

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(H-2K1-Lrp5/Fkbp1a,-luc*)#Dmps/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(H-2K1-Lrp5/Fkbp1a,-luc*)#Dmps

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased prostate gland adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0009220

文献

http://purl.org/net/cito/citesAsAuthority

• Julienne L. Carstens, et.al., FGFR1-WNT-TGF-β signaling in prostate cancer mouse models recapitulates human reactive stroma., Cancer research, 2014, 74
  http://rdf.ncbi.nlm.nih.gov/pubmed/24305876
• Payam. Shahi, et.al., Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis., PloS one, 2012, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/22303459