increased adenocarcinoma incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>

http://metadb.riken.jp/0009308I129P2OlaHsd129S4SvJaeKrastm4TyjKrasTrp53tm1BrnTrp53tm1BrnTrp53tm1BrnKrastm4TyjKras

increased adenocarcinoma incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brn>|Kras<tm4Tyj>|Kras<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0009308

文献

http://purl.org/net/cito/citesAsAuthority

• Erica L. Jackson, et.al., The differential effects of mutant p53 alleles on advanced murine lung cancer., Cancer research, 2005, 65
  http://rdf.ncbi.nlm.nih.gov/pubmed/16288016