increased duodenum adenocarcinoma incidence_B3gnt6<tm1Lx>/B3gnt6<tm1Lx>,C1galt1<tm1.1Rpmc>/C1galt1<tm1.1Rpmc>,Tg(Vil-cre/ERT2)23Syr/0

http://metadb.riken.jp/0009311I129S1SvC57BL6C57BL6JDBA2B3gnt6tm1LxB3gnt6tm1LxC1galt1tm11RpmcC1galt1tm11RpmcTgVilcreERT223Syr0C1galt1tm11RpmcB3gnt6tm1LxTgVilcreERT223Syr

increased duodenum adenocarcinoma incidence_B3gnt6<tm1Lx>/B3gnt6<tm1Lx>,C1galt1<tm1.1Rpmc>/C1galt1<tm1.1Rpmc>,Tg(Vil-cre/ERT2)23Syr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:2151071
• transgene insertion 23, Sylvie Robine
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053810
• UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
  http://metadb.riken.jp/db/mgi_rdf/MGI:3039603

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• B3gnt6<tm1Lx>/B3gnt6<tm1Lx>,C1galt1<tm1.1Rpmc>/C1galt1<tm1.1Rpmc>,Tg(Vil-cre/ERT2)23Syr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• C1galt1<tm1.1Rpmc>|B3gnt6<tm1Lx>|Tg(Vil-cre/ERT2)23Syr

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6 * C57BL/6J * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased duodenum adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0009311

文献

http://purl.org/net/cito/citesAsAuthority

• Nan. Gao, et.al., Loss of intestinal O-glycans promotes spontaneous duodenal tumors., American journal of physiology. Gastrointestinal and liver physiology, 2016, 311
  http://rdf.ncbi.nlm.nih.gov/pubmed/27229122